Data
Official data in SubjectManager for the following academic year: 2023-2024
Course director
-
Dr. Katalin SIPOS
associate professor,
Department of Pharmaceutical Biology -
Number of hours/semester
lectures: 28 hours
practices: 0 hours
seminars: 14 hours
total of: 42 hours
Subject data
- Code of subject: OPO-G1B-T
- 3 kredit
- Pharmacy
- Med.-biol. theoretical module and practical skills modul
- spring
OPA-L1E-T completed , OPA-ALK-T completed
Exam course:yes
Course headcount limitations
min. 1
Topic
The two-semester biochemistry course provides the essential fundamental biochemistry knowledge for the pharmaceutical students. This course deals with the metabolic pathways of the living cell: the reactions, steps and regulation of these pathways. In the first semester students will be introduced to the life of the basic synthetic and anabolic biochemical pathways and they will study how energy is produced in the cell. We will pay special attention to enzymes: their features, regulations, roles in the drug metabolism and action.
Lectures
- 1. Introduction - Dr. Sipos Katalin
- 2. Thermodynamics, biochemical reactions - Jánosa Gergely
- 3. Biomembranes. Transport processes I - Dr. Sipos Katalin
- 4. Transport processes II - Dr. Sipos Katalin
- 5. Enzymes: characteristics, types, catalytic activities - Pap Ramóna
- 6. Channels, action potential - Dr. Sipos Katalin
- 7. Basic regulatory mechanisms in metabolism - Dr. Sipos Katalin
- 8. Glycolysis - Dr. Sipos Katalin
- 9. Gluconeogenesis - Dr. Farkas Viktória
- 10. Glycogen metabolism - Dr. Farkas Viktória
- 11. Cori cycle - Dr. Farkas Viktória
- 12. Pentose phosphate pathway - Dr. Farkas Viktória
- 13. Metabolism of complex carbohydrates - Dr. Sipos Katalin
- 14. Pyruvate dehydrogenase complex - Dr. Farkas Viktória
- 15. Citric acid cycle - Dr. Sipos Katalin
- 16. Mitochondrial transport processes - Dr. Farkas Viktória
- 17. Terminal oxidation, ATP synthesis I - Dr. Farkas Viktória
- 18. Terminal oxidation, ATP synthesis II - Dr. Farkas Viktória
- 19. Degradation of lipids - Dr. Sipos Katalin
- 20. Ketone bodies - Pap Ramóna
- 21. Biosynthesis of fatty acids - Dr. Sipos Katalin
- 22. Biosynthesis of complex lipids - Dr. Sipos Katalin
- 23. Cholesterol metabolism I - Dr. Farkas Viktória
- 24. Cholesterol metabolism II - Dr. Farkas Viktória
- 25. Characterization of amino acids - Pap Ramóna
- 26. Nucleic acids: building blocks, structures - Pap Ramóna
- 27. Preparation for exam - Dr. Sipos Katalin
- 28. Preparation for exam - Dr. Sipos Katalin
Practices
Seminars
- 1. Macromolecules in biochemistry
- 2. Nutrition and vitamins in biochemistry
- 3. Carbohydrates: biochemical characterization. Carbohydrates in the extracellular space
- 4. Clinical importance of carbohydrates
- 5. Regulation of enzymes
- 6. Enzymekinetics. Inhibition of enzymes
- 7. Structure, folding and degradation of proteins
- 8. Lipids: phospholipids, sphingolipids, cholesterol, fatty acids
- 9. Clinical importance of lipids
- 10. Clinical consequences of terminal oxidation.
- 11. Carbohydrate metabolism
- 12. Lipid metabolism
- 13. Enzyme inhibiting drugs
- 14. Preparation for exam
Reading material
Obligatory literature
Literature developed by the Department
The materials of the lectures and seminars will appear on Neptune.
Notes
The e-notes of Biochemistry will appear on Neptune.
Recommended literature
Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences
Raymond S. Ochs: Biochemistry
Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There is no written mid-term exam.
Making up for missed classes
According to personal agreement
Exam topics/questions
There are no given exam questions. The topics of the exam will be the materials of lectures and seminars.
Examiners
- Dr. Farkas Viktória
- Dr. Pandur Edina
- Dr. Sipos Katalin
Instructor / tutor of practices and seminars
- Dr. Farkas Viktória
- Dr. Horváth Adrienn
- Dr. Pandur Edina
- Dr. Sipos Katalin
- Jánosa Gergely
- Pap Ramóna