Data
Official data in SubjectManager for the following academic year: 2023-2024
Course director
-
Dr. Katalin SIPOS
associate professor,
Department of Pharmaceutical Biology -
Number of hours/semester
lectures: 14 hours
practices: 0 hours
seminars: 28 hours
total of: 42 hours
Subject data
- Code of subject: OTV-BIC1-T
- 3 kredit
- Biotechnology BSc
- Specialised Core Module modul
- spring
OTN-GENC-T completed , OTV-SEBI-T completed
Exam course:yes
Course headcount limitations
min. 1
Topic
In the Biochemistry I subject, the students will study the macromolecules, which build up the eukaryotic cells. They learn about the most important energy providing pathways (glycolysis, citric acid cycle, fatty acid degradation, photosynthesis), and the major biosynthetic pathways (glycogen, lipid, amino acid and nucleotide synthesis). In addition, we will deal with the basic biochemistry of prokaryotic and plant cells, as they are widely used in biotechnology.
Lectures
- 1. Introduction. Metabolic pathways - Dr. Sipos Katalin
- 2. Glycolysis - Dr. Sipos Katalin
- 3. Gluconeogenesis. Cori cycle - Dr. Farkas Viktória
- 4. Metabolism of glycogen - Dr. Farkas Viktória
- 5. Pyruvate dehydrogenase complex - Dr. Farkas Viktória
- 6. Pentose phosphate pathway - Pap Ramóna
- 7. Degradation of fatty acids - Dr. Sipos Katalin
- 8. Citric acid cycle - Dr. Sipos Katalin
- 9. Terminal oxidation, ATP synthesis - Dr. Farkas Viktória
- 10. Ketone bodies - Dr. Farkas Viktória
- 11. Biosynthesis of fatty acids - Dr. Farkas Viktória
- 12. Metabolism of cholesterol - Dr. Farkas Viktória
- 13. Amino acids - Pap Ramóna
- 14. Nucleic acids: building blocks, structure - Pap Ramóna
Practices
Seminars
- 1. Basic regulatory processes of metabolism
- 2. Thermodynamics, biochemical reactions
- 3. Carbohydrates
- 4. Carbohydrates
- 5. Enzymology - the basics
- 6. Enzyme kinetics
- 7. Inhibition of enzymes
- 8. Regulation of enzymes
- 9. Enzymes in biotechnology
- 10. Enzymes in biotechnology
- 11. Importance of carbohydrates in biotechnology
- 12. Metabolism of complex carbohydrates
- 13. Lipids
- 14. Importance of lipids in biotechnology.
- 15. Anaplerotic processes.
- 16. Metabolism of complex lipids.
- 17. Clinical importance of terminal oxidation.
- 18. Carbohydrates – summary.
- 19. Energy production in plants.
- 20. Carbohydrate metabolism in plants.
- 21. Energy production in bacteria
- 22. Energy production in bacteria
- 23. Lipids, energy production – summary
- 24. Lipids, energy production – summary
- 25. Structure of proteins.
- 26. Purification of proteins.
- 27. Consultation
- 28. Consultation
Reading material
Obligatory literature
Literature developed by the Department
The materials of the lectures and seminars will appear on Neptune.
Notes
Recommended literature
Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences
Raymond S. Ochs: Biochemistry
Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There is no written mid-term exam in the semester.
Making up for missed classes
According to personal agreement
Exam topics/questions
There are no given exam questions. The topics of the exam will be the materials of lectures and seminars.
Examiners
- Dr. Farkas Viktória
- Dr. Pandur Edina
- Dr. Sipos Katalin
Instructor / tutor of practices and seminars
- Dr. Farkas Viktória
- Dr. Horváth Adrienn
- Dr. Pandur Edina
- Dr. Sipos Katalin
- Jánosa Gergely